With infertility populations in the developed world rapidly aging, treatment of diminished ovarianreserve (DOR) assumes increasing clinical importance. Dehydroepiandrosterone (DHEA) has been reported toimprove pregnancy chances with DOR, and is now utilized by approximately one

Objective: The objective of this study was to provide evidence that the transformation of DHEA into bothandrogens and/or estrogens locally in cells of the three layers of the vagina (epithelium, lamina propria, andmuscularis) would have

Objective To examine the effect of intravaginal dehydroepiandrosterone (DHEA) on pain at sexual activity (dyspareunia) identified as the most bothersome symptom of vaginal atrophy in postmenopausal women atboth screening and day 1. Methods This prospective,

Emerging preclinical and clinical evidence suggests that pregnenolone may be a promising novel therapeutic candidate in schizophrenia. Pregnenolone is a neurosteroid with pleiotropic actions in rodents that include the enhancement of learning and memory, neuritic

We investigated the relationship between oxidative stress and poor oocyte quality and whether the antioxidant melatonin improves oocyte quality. Follicular fluid was sampled at oocyte retrieval during in vitro fertilization and embryo transfer (IVF-ET). Intrafollicular

The primary purpose of this six-week survey study of women currently taking compounded bioidentical hormone replacement therapy was to determine if compounded bioidentical hormone replacement therapy relieves symptoms of menopause and is well tolerated. The